• Biotrexate 500mg Injection is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus
• It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease
• Biotrexate 500mg Injection may be used alone or in combination with other medicines
• You should take it exactly as your doctor has advised
• Taking too much of it can cause serious side effects
• It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to
• You should avoid consumption of alcohol while taking this medicine as it may increase your risk of liver damage.
• The most common side effects of this medicine are ulcerative stomatitis, hairloss, low blood cell count, increased liver enzymes, nausea, and abdominal distress
• Your doctor may advise you to take folic acid to reduce some of these
• If they do not go away or get worse, tell your doctor
• There may be ways of preventing or reducing these effects
• This medicine may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys
• Your doctor may perform several tests such as blood tests, X-rays, and physical examinations both before and during treatment with this medicine to check for these.
• Before taking it, tell your doctor if you have problems related to the stomach, liver, or kidney, or are taking any medicines to treat infections
• Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using
• This medicine is not recommended during pregnancy or while breastfeeding as it may harm the baby.

Uses of Biotrexate 500mg Injection

• In Treatment of Cancer Biotrexate 500mg Injection works by slowing the growth of cancer cells in the body
• It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer
• It may be given alone or in combination with other medicines
• It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor
• You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated
• In Treatment of Rheumatoid arthritis Biotrexate 500mg Injection belongs to a group of medicines called antimetabolites
• It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked
• It is not a first-line treatment
• It works by reducing the body's immune system, this decreases swelling, reduces pain, stiffness, and improves function
• Take it exactly as prescribed and for as long as it is prescribed to get the most benefit
• Do not take more than you should
• It may take several months to become fully effective
• In Treatment of Psoriasis Biotrexate 500mg Injection belongs to a group of medicines called antimetabolites
• It may be used to treat severe psoriasis when other treatments have not worked
• Psoriasis is a condition where the skin cells in the body grow too quickly
• Biotrexate 500mg Injection works by killing these fast-growing cells
• It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor
• Take it exactly as prescribed and for as long as it is prescribed to get the most benefit
• DO NOT take more than you should
• It may take several months to become fully effective
• You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated
• In Treatment of Crohn’s disease Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines
• The most common symptoms are diarrhea and pain in your abdomen
• Biotrexate 500mg Injection helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

Missed Doses

If you miss a dose of Biotrexate 500mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Frequestly asked Questions

Common and Known Side effects of Biotrexate 500mg Injection

• Ulcerative stomatitis
• Nausea
• Abdominal pain
• Increased liver enzymes
• Hair loss
• Decreased blood cells (red cells
• white cells
• and platelets)