• A Cox 450mg Capsule is an antibiotic, used in the treatment of all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body
• It may be used alone or in combination with other medicines to fight serious infections
• A Cox 450mg Capsule may also be given to people who are carriers (people who are infected, yet do not show any signs and symptoms of infection)
• It should be taken on an empty stomach, at least 30 minutes before a meal or 2 hours after a meal
• It should be taken in the dose and duration as advised by the doctor
• It is better to take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed
• Stopping it early may make the infection to come back and harder to treat.
• Some people may develop side effects like low blood platelets, headache, dizziness, vomiting, nausea, and fever
• These side effects are usually temporary and go away during treatment as your body adjusts to the medicine
• Consult your doctor if these side effects bother you or will not go away.
• Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any medicine
• You may be regularly monitored with blood tests for liver function tests while using this medicine.

Uses of A Cox 450mg Capsule

• In Tuberculosis (TB) A Cox 450mg Capsule is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well
• It kills as well as stops the growth of infection causing bacteria and helps in treating the infection
• Take it in the dose and duration advised by the doctor
• Your symptoms may improve before the infection is completely cured
• Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen
• Follow your doctor’s instructions carefully to get maximum benefit.

Missed Doses

If you miss a dose of A Cox 450mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Frequestly asked Questions

Is rifampin a penicillin/amoxicillin/sulfa drug?

No. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has a structure and mechanism of action different from penicillin or amoxicillin (amoxicillin belongs to the class of penicillin antibiotics). The chemical structure and mechanism of action of rifampin is different from sulfa drugs

Is rifampin bacteriostatic or bactericidal?

Rifampin is a bactericidal drug. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for important life processes in the bacteria, thereby killing the bacteria

Is rifampin an inducer or inhibitor?

Rifampin is an inducer (increases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body

What is R-cin 600 used for?

R-cin 600 is a trade name for active drug rifampin 600 mg. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It is also used in the prevention of meningococcal meningitis and Haemophilus influenza infections. It may also be used in combination with other drugs to treat infections-Brucellosis, Legionnaires disease or serious staphylococcal infections

What is R-cinex/Macox plus/R-cinex 600?

R-cinex and Macox plus are trade names for a combination of active drugs rifampin and isoniazid. It is used in the treatment of tuberculosis. R-cinex 600 and Macox plus contains 600 mg of active drug rifampin and 300 mg of active drug isoniazid

Can I take rifampin with ibuprofen/acetaminophen (Tylenol)?

Rifampin has no known serious drug interaction with ibuprofen or acetaminophen (trade name: Tylenol). Inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Does rifampin cause weight gain/weight loss/ hair loss/ constipation/ yeast infection?

No. Changes in body weight, hair loss or triggering constipation are not among the known side effects of rifampin. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has no known effect on causing yeast infections

Does rifampin cause headaches?

Yes. Headache is a possible side effect of rifampin

Does rifampin change urine color/turn urine orange?

Yes. Taking rifampin may change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful

Does rifampin cause liver damage?

Rifampin is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with rifampin. Taking drugs like saquinavir, ritonavir with rifampin can cause severe liver damage. Do consult your doctor if you have any liver problem before taking rifampin.

Common and Known Side effects of A Cox 450mg Capsule

• Low blood platelets
• Dizziness
• Vomiting
• Nausea
• Fever
• Abdominal pain
• Skin rash
• Hepatitis (viral infection of liver)
• Headache
• Chills
• Paradoxical reactions
• Increased aspartate aminotransferase
• Increased alanine aminotransferase
• Increased bilirubin in the blood